RESEARCH

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Small-angle Scattering

Actin

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Joanna K. Krueger

Assistant Professor

Biochemistry

(704) 687-4913 (voice)
(704) 687-3151 (FAX)
jkkruege@uncc.edu

 

 

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Recent Publications

Fengwei Bai, Terrence Town, Deepti Pradhan, Jonathan Cox, Ashish,  Michel Ledizet, John F. Anderson, Richard A. Flavell, Joanna K. Krueger,  Raymond A. Koski, and Erol Fikrig.  (2007) "Antiviral peptides targeting the West Nile Envelope Protein" J. Virology. In press.

Renu Garg, Ignacio J. Juncadella, Nandhini Ramamoorthi, Ashish, Shobana K. Ananthanarayanan, Venetta Thomas, Mercedes Rincon, Joanna K. Krueger, Erol Fikrig, Christopher M. Yengo and Juan Anguita. 2006. Cutting Edge: CD4 is the receptor for the tick saliva protein, Salp15. The Journal of Immunology. J. Immunology 177(10):  6579-6583.  

Gautam, J.K.; Ashish; Comeau, L.D., Krueger, J.K., and  Smith, M.F. Jr. (2006) Structural and Functional Evidence for the role of the TLR2 DD loop in TLR1/TLR2 Heterodimerization and  Signaling. J. Biol. Chem. 281(40):30132-42.

Ashish; Garg, R.; Anguita, J.; Krueger, J.K. (2006) Binding of Full-length HIV-1 gp120 to CD4 Induces Structural Reorientation Around the gp120 Core. Biophys. J. 91(6): L69-71L.

Krueger J. K. and Wignall, G. D. (2004) “Small Angle Neutron Scattering from Biological Molecules”. In Neutrons in Biology - Techniques and Applications (J. Fitter, T. Gutberlet, J. Katsaras, Eds.) Springer Publications Biophysical Studies Series, Chapter 8 pp. 127-160.

Heller, W. T., Krueger, J. K., and Trewhella, J. (2003) “Further Insights into Calmodulin-Myosin Light Chain Kinase Interaction from Solution Scattering and Shape Restoration". Biochemistry 42: 10579-588.

Heller, W., Trewhella, J., and J. K. Krueger. (2002) “Small-angle Solution Scattering Reveals Information on Conformational Dynamics in Calcium Binding Proteins and in Their Interactions with Regulatory Targets”. Invited article for Methods of Molecular Biology. (Calcium-binding Protein Protocols, v. 2). H.J. Vogel, Ed. Vol 173, pp. 137 – 160. Humana Press.

Krueger, J. K., Gallagher, S. C., Zhi, G., Geguchadze, R., Persechini, A., Stull, J. and Trewhella, J. (2001, accelerated publication) “Activation of Myosin Light Chain Kinase Requires Translocation of Bound Calmodulin” J. Biol. Chem. 276(7): 4535-4538.  

Krueger, J. K., Gallagher, S. C., Wang, A., and Trewhella, J. (2000) “Calmodulin Remains Extended upon Binding to Smooth Muscle Caldesmon: A Combined Small-Angle Scattering and Fourier Transform Infrared Spectroscopy Study.” Biochemistry, 39(14): 3979-3987.

Krueger, J., McCrary, B., Wang, A. H.-J., Shriver, J. W., Trewhella, J., and Edmondson, S. P.  (1999) “Solution Structure of Sac7d/DNA Complex Studied by Small-Angle X-ray Scattering”. Biochemistry 38(32): 10247-10255.  

Trewhella, J., Gallagher, S. C., Krueger, J. K., and Zhao, J. (1998) “Neutron and X-ray Solution Scattering Provide Insights into Biomolecular Structure and Function”. Science Progress 81(2): 101-122.

Krueger, J. K., Bishop, N. A., Blumenthal, D. K., Zhi, G., Beckingham, K., Stull, J. and Trewhella, J. (1998) “Calmodulin Binding to Myosin Light Chain Kinase Begins at Substoichiometric Ca2+ Concentrations: A Small-Angle Scattering Study of Binding and Conformational Transitions” Biochemistry 37(51): 17810-17817.

Stull, J. T., Lin, P. J., Krueger, J. K., Trewhella, J., and Zhi, G. (1998) “Myosin Light Chain Kinase:  Functional Domains and Structural Motifs”. Acta Physiol. Scand. 164: 471-482.

Improta, S., Krueger, J. K., Gautel, M., Atkinson, R., Lefevre, J.-F., Moulton, S., Trewhella, J. and Pastore, A. (1998) “The Assembly of Immunoglobulin-like Modules in Titin:  Implications For Muscle Elasticity”.  J. Mol. Biol. 284(3): 761-777.

Krueger, J. K., Zhi, G., Stull, J.T., and Trewhella, J. (1998) “Neutron Scattering Studies Reveal Further Details of the Ca2+/Calmodulin-Dependent Activation Mechanism of Myosin Light Chain Kinase”. Biochemistry 37(40): 13997-14004.

Krueger, J.K., Olah, G. A., Rokop, S., Zhi, G., Stull, J. T. and Trewhella, J. (1997) “Structures of Calmodulin and a Functional Myosin Light Chain Kinase in the Activated Complex: A Neutron Scattering Study.” Biochemistry 36: 6017-23.

Stull, J. T., Kamm, K. E., Krueger, J. K., Lin, P.-J., Luby-Phelps, K.,  and  Zhi, G. (1997) “Ca2+/Calmodulin-dependent Myosin Light Chain Kinase”. Chapter for Advances in Second Messengers and Phosphoproteins  (J. Corbin and S. Francis, Eds.) Vol. 31, pp. 141-149, Raven Press, New York.

Stull, J. T., Krueger, J. K., Kamm, K. E., Gao, Z.-H., Zhi, G. and Padre, R. C. (1996) “Myosin Light Chain Kinase”. In: Biochemistry of Smooth Muscle Contraction  (Barany, M., Ed.) pp. 119-128, Academic Press, Inc., San Diego.

Krueger, J. K., Padre, R. C., and Stull, J. T. (1995) “Intrasteric Autoinhibition of Myosin Light Chain Kinase” J. Biol. Chem.  270(28): 16848-853.

Stull, J. T., Krueger, J. K., Zhi, G. and Gao, Z. -H. (1995) “Molecular Properties of Myosin Light Chain Kinases”. In: International Symposium on Regulation of the Contractile Cycle in Smooth Muscle. April 26, 1995, MIE, Japan.

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